TCA cycle:
1.pyruvate+ CoA+NAD+ -> acetyl CoA+co2+NADH
pyruvate dehydrogenase
E1:pyruvate dehydrogenase complex,TPP(thiamine pyrophosphate),oxidative decarboxlation of pyruvate.
E2:dihyroxylipoyl transacetylase,lipoamide,tranfer of acetly to CoA.
E3:dihyroxy lipoyl dehyrogenase,FAD,regeneration of oxidized lipoamide.
place:the playing ground
E1:badminton court
paru is waiting with hydrogen cylinders tied to his back.he's playing badminton,peeche se bharoon aake kehta hai...TaPPu!paru gives himthis-is-badminton-not-basketball-looks.
E2:tennis court
2 botal paani(1 on each pole of the net) aur ek lolipop(in the centre of the net) padi hai tennis court mein.
dihyroxy lipoly
aur phir bobby darling with acetic acid aati hai,to play tennis.
transacetylase.
E3:basketball court
dihyroxy lipoyl dehydrogenase.
simply:decarb->transfer of acetyl->lipoyl ki marammat by hydrogen to FAD,then to NAD.
2.the cycle:
from:lt3->boys lu->generator waali jagah->mandir->fountain->buletin board->uniform shop->photcopy place
lt3:citrate,synthase.
entry of LT2 turned into a huge citrus fruit,orange ya lemon.
aur lemon ke bagal mein,synth par,bahut tez tez moozic baja raha hai.(synthase)
boys lu:isocitrate,acotinase
me sleeping in the boys room(i so).
with me is Acon,wohi gande gaane gaane waala.
generator room:alpha keto glutarate,dehydrogenase
since the generator waali jagah is undergound,as you open its door,bahoot saare keet makoode slam into your face.aur tum neeche jhank ke dekte ho..you see a lot of water in it.(hydro)
madir:succinyl CoA,dehydrogenase
mandir mein prashad mein sabko lolipop milti hai to suck.
of course,yahn bhi dhaer saara paani hai.that has come from a well(kuan)(CoA)
Fountain:succinate,sythetase
fountain pe nate log(dg,beeps and riccha) are eating a lolipop.(succinate)
peehce background music for this grand event is being done by bharoon standing insde the fountain,on sythesizer,teasing all of them.
buletin board:fumerate,dehydrogenase
bultein board pe bahut saare logon ko crucify kara gaya hai,but unmein se sirf kuch(few) hi mare hain.
and you revve the survivors using water(dehydrogenase)
uniform shop:malate,fumarase
a few people are counting money(maal) outside the uniform shop.
unme se kuch,mar jaate hain.ginte ginte.
photocopy shop:oxaloacetate,dehydrogenase
photocopy waale bhaiya ke pass,ek bael(ox) khadi hai.
aur woh usko paani pilaane ko aapko bol rahe hain.
Regulation:
1.at pyruvate dehydrogenase.
swithed off when energy charge is high
- acetyl CoA,ATP,NADH activate kinase.
+ ADP,Pyruvate,,NAD+(deactivate kinase) Ca2+ activate phosphatase.
2.Isocitrate dehydrogenase
+ADP
-ATP,NADH
3.Alpha keto glutarate
-succinyl coa,NADH,ATP
Arsenite poisoning
arsenite ind to e2.
BAL(2,3 dimercaptopropanol)(23(neem)DMP)(dimpy naam ki ladki) used to relieve the arsenite.
glyoxylate cyle
Acetate+CoASH+ATP->Acetly CoA+AMP+ppi
cit->isocit->glyoxylate->malate->OAA->cit
acotinase,isocitrate lysase,matale synthase,malate dehydrogenase,citrate synthase
Monday, September 29, 2008
saare GLUT's ke naam
once again:
1=danda
2=duck
3=heart
4=chair
5=hook
6=hockey
7=bread pakora(non cafe waala)
8=chasma
9=lolipop
GLUT:glutton yaani babban,FANKEE,bharoon and sameer
all this in front of LRC
GLUT1 and 3:basal uptake of glucose.
sameer ke paaron(base) pe glucose girta hai aur woh apne aap hi paero se "saukh"(absorb) liya jaata hai.the he says i am full..
then...ek "dande" se apne "dil" par ghae ghae karta hai.
GLUT 2:liver and pancreas.
liver se glucose uptake badhaana.(removes glucose from blood)
pancreas se insulin nikalwaana.
glut 2 matlab baban jiske sar par "duck" hai.
and he holds and appliation for "leave"r aur sameer ko dekhte hi usne appication andar daal li,of course bag mein.(uptake of glucose)
aur phir andar se usne ek pan(creas) nikaala aur sameer ke sir pe dee maara..jisse uska ghae ghae band ho gaya.sameer thanks babban.
GLUT 4:muscle and fat cells.
bharoon(GLut 4) jo ki "chair" pe baitha hai kyunki woh thak gaya hai,aur usko bhook lagi hai aur jo apne dolle(muscle) dikha raha hota hai aur naina se dolle compare kar raha hota hai
baban(yaani insulin) ko dekh kar ek dam khada ho jaata hai.
GLUT 5:primary fructose transporter
fankee,pirate waala "hook",lekar sabke baag check karta hai..for apple(fructose hota hai na usme).
1=danda
2=duck
3=heart
4=chair
5=hook
6=hockey
7=bread pakora(non cafe waala)
8=chasma
9=lolipop
GLUT:glutton yaani babban,FANKEE,bharoon and sameer
all this in front of LRC
GLUT1 and 3:basal uptake of glucose.
sameer ke paaron(base) pe glucose girta hai aur woh apne aap hi paero se "saukh"(absorb) liya jaata hai.the he says i am full..
then...ek "dande" se apne "dil" par ghae ghae karta hai.
GLUT 2:liver and pancreas.
liver se glucose uptake badhaana.(removes glucose from blood)
pancreas se insulin nikalwaana.
glut 2 matlab baban jiske sar par "duck" hai.
and he holds and appliation for "leave"r aur sameer ko dekhte hi usne appication andar daal li,of course bag mein.(uptake of glucose)
aur phir andar se usne ek pan(creas) nikaala aur sameer ke sir pe dee maara..jisse uska ghae ghae band ho gaya.sameer thanks babban.
GLUT 4:muscle and fat cells.
bharoon(GLut 4) jo ki "chair" pe baitha hai kyunki woh thak gaya hai,aur usko bhook lagi hai aur jo apne dolle(muscle) dikha raha hota hai aur naina se dolle compare kar raha hota hai
baban(yaani insulin) ko dekh kar ek dam khada ho jaata hai.
GLUT 5:primary fructose transporter
fankee,pirate waala "hook",lekar sabke baag check karta hai..for apple(fructose hota hai na usme).
learn glyconeo
farak b/t nea and glycolysis:
subsrate:add OAA
enzymes:(stored in computer lab entry)(computer-->matrix-->neo??)
1.pyruvate carboxylase:lockers,
paru wait carbon copy ke saath.
2.PEP carboxykinase
PEPCK
:biochem lab ka door jo kabhi nahi khulta,
registrar giving "pep" talk,to cutta kameena(me and fankee)
3.F16BPtase
:boys,loo ki entry,
wahan par fan ke ek fresher ko exhaust fan par latka kar,tasing,oops teasing ho ri hai.
4.G6Ptase
balcony,
glucose ki kami ke karan,teasing karte hue bande,thak kar neeche gir jaate hain.
haan pata hai,marne peetne ki baat jab tak na aaye tab tak mazza kahan aata hai.
entry points yaad karne ka tareeka:
computer lab ke andar
1.lactate(doodh)
at:entry karke right ko jo board aata hai uspar.doodh gira hua hai.
aur woh board "kora"(blank tha...)tabhi wahan par "cori" cycle hoti hai.
muscle
G->P->L
liver:
l->P->G
6 atp lagte hain,6=>hockey stick.board ke side mein ek hockey stick padi hui hai.uspar likha hai,incase of yamuna,use hockey stick.
2.amino acid
except luesine,lysine:leusingh is king,ly has seen it all.
place:register,jispar sign karna padta hai,jo ek printer ke upar pada rehta hai.
Muscle
G->P->ala
alanine transaminase.
(trans=>bobby darling,whan kar printer par batihi/baitha hua hai)
Liver:
Ala->urea(potty jokes)
(i won't say it,nahi to tum log meri jaan khaa jaoge,but you can understand,how to relate bobby darling to potty)
ala->p->G
3.Glycerol
at:the gaurds who sits in the comp lab,abhi tak pata ni chal paaya kyun baithta hai.
glcerol->glycerol phospate->Dhappa!
so the gaurd has been sitting there for so long that in order to preserve him,we put glycerol over him.
and since wo wahan par bade dino se batiha hota hai,gas to banegi hi..so phospate:fusfate.
aur phir usko jagaane ke liye ek banda peeche se usko dhappa karta hai!
kinase,dehydrogenase.
4.Propionate
at:the room where all the teachers sit in the coputer room.
propionyl CoA->D-methylmalonyl CoA->L-methylmalonyl CoA->Succinyl CoA
PC->DMC->LMC->SC
melon oil!
PC lekar baithe bande,MCD(bulldozer) ke intezaar mein,
kahat "L"aalu(see me as the operator of bulldozer) suno bhayee c2,socks(soccinyl CoA) ke bazar mein.
(meri socks ki badu se bulldozer ki zarooratni padi!)
(haan haan marle gande jokes,aur kab mauka milega tujhe??)
enzymes:carboxlyase,epimerase,mutase.
subsrate:add OAA
enzymes:(stored in computer lab entry)(computer-->matrix-->neo??)
1.pyruvate carboxylase:lockers,
paru wait carbon copy ke saath.
2.PEP carboxykinase
PEPCK
:biochem lab ka door jo kabhi nahi khulta,
registrar giving "pep" talk,to cutta kameena(me and fankee)
3.F16BPtase
:boys,loo ki entry,
wahan par fan ke ek fresher ko exhaust fan par latka kar,tasing,oops teasing ho ri hai.
4.G6Ptase
balcony,
glucose ki kami ke karan,teasing karte hue bande,thak kar neeche gir jaate hain.
haan pata hai,marne peetne ki baat jab tak na aaye tab tak mazza kahan aata hai.
entry points yaad karne ka tareeka:
computer lab ke andar
1.lactate(doodh)
at:entry karke right ko jo board aata hai uspar.doodh gira hua hai.
aur woh board "kora"(blank tha...)tabhi wahan par "cori" cycle hoti hai.
muscle
G->P->L
liver:
l->P->G
6 atp lagte hain,6=>hockey stick.board ke side mein ek hockey stick padi hui hai.uspar likha hai,incase of yamuna,use hockey stick.
2.amino acid
except luesine,lysine:leusingh is king,ly has seen it all.
place:register,jispar sign karna padta hai,jo ek printer ke upar pada rehta hai.
Muscle
G->P->ala
alanine transaminase.
(trans=>bobby darling,whan kar printer par batihi/baitha hua hai)
Liver:
Ala->urea(potty jokes)
(i won't say it,nahi to tum log meri jaan khaa jaoge,but you can understand,how to relate bobby darling to potty)
ala->p->G
3.Glycerol
at:the gaurds who sits in the comp lab,abhi tak pata ni chal paaya kyun baithta hai.
glcerol->glycerol phospate->Dhappa!
so the gaurd has been sitting there for so long that in order to preserve him,we put glycerol over him.
and since wo wahan par bade dino se batiha hota hai,gas to banegi hi..so phospate:fusfate.
aur phir usko jagaane ke liye ek banda peeche se usko dhappa karta hai!
kinase,dehydrogenase.
4.Propionate
at:the room where all the teachers sit in the coputer room.
propionyl CoA->D-methylmalonyl CoA->L-methylmalonyl CoA->Succinyl CoA
PC->DMC->LMC->SC
melon oil!
PC lekar baithe bande,MCD(bulldozer) ke intezaar mein,
kahat "L"aalu(see me as the operator of bulldozer) suno bhayee c2,socks(soccinyl CoA) ke bazar mein.
(meri socks ki badu se bulldozer ki zarooratni padi!)
(haan haan marle gande jokes,aur kab mauka milega tujhe??)
enzymes:carboxlyase,epimerase,mutase.
learn Glycogenolysis and glycogenlysis
Glycogenolysis
4 steps in biotech labs.
1.glycogen phosphorlyase
glycogen+pi->g1p+Glycogen
at:VAC.
VAc ko khola to usmein se bahut saari badbu(fus) bahar aayi and uske andar bahut saara fur
rakha hua tha,jo ek dande(1) par latka hua tha.fusfur.
2.debranching:
mol bio ki lab entry par,jahan humein microbio ke paper dikhaaye gaye the.
phoshorylase stops 4 residues prior to the 1,6 link.
tranferase:transfers 3 residues
alpha-1,6-glucosidase releases the single glucose unit.
hexokinase phophorylates it.
stop->tranfer->release->fusfur.
1.so as you were going to the biochem lab,you stop at the mol bio lab and say:whats it?
2.andar jaa kar,you see ki sink ke pass,kissi teacher ka tranfer order pada hua hai.
3.you were happy ki ye biochem teacher ka hai,but then see ki ye to agle saal ka hai.so you
release it.you release it to the other side,sidase.
4.the room suddenly became smelly(fus) and you decide to go away as the lab ass comes to
with a hockey stick.(6=>hexokinase)
(ab mujhe mat kehna,what can i do,jab phosphorlyation ka fus hi ban paata hai)
3.phosphogluco mutase
g1p->g6p.
cold storage mein,GMO 39 pada hua hai.woh mutant variety hai.
4.G6p->g+pi
done by glucose 6 phoshatase.
transported out by GLUT 2.
how dearly you wish ki biochem lab phat jaaye,with all teachers inside.
Von girke's disease
lack of glucose-6-phosphatase.
so glucose-6p cannot be released as glucose into the blood.
glycogenesis
from washing areain biotech labs to the mtech labs.
overall reaction
glycogen(n)+UDP-glucose->glycogen(n+1)+UDP
by glycogen synthase
by the idea of Hi(a teacher..name confidential) the washing area would also serve as a south
indian resturant.so uska naam udippi(UDP) rakh diya gaya.wahan ki main dish glucond hoti
hai.aur peehce music dene ke liye synthsizer(synth) ka bhi ue kiya jaa raha hai.
part of reactions:
UTP+glucose->UDP glucose+PPi
by UDP glucose pyrophosphorylase
thermo labki entry pe.spagetti hair khada hai(wohi tissue paper and water waala,jiski beti
ki shaadi thi).
uske bete ka Unit test(UT-P) aane waala hai,to woh uski copy le kar khada hai.aur fankee k
paer("pyro"phosphatase) padta hai,to teach his son some english.(what did you just said?)
PPi->2Pi
by inorganic pyrophosphatase
instumentation lab ki entry par,woh dantne waala lab ass khada hai(wahi jiske saamne bharoon
ne psst pss..idhar aa kiya tha).
so you say to him to let you "in",aur sirf itna sunte hi woh bhi tumhaare paer par gir
kar,phat jaata hai.
branching is done by glycosyl-(4-6)-transferase
at:jahan par pittete rakhe hote hain.
us pippete stand emin ek jagah hockey(6) padi hoti hai,aur ek jagah chair(4),to teacher aake
bolti hai,uko interchange kardo,i.e.,transfer kardo,kyunki woh khud ni kar sakti,unke ghar
mein koi "ill"(glyco"syl")hai.
new glycogen cannot be formed without primer.
primer banaane ka enzyme:glycogenin
mircowave par zung lagne lagta hai to uspar primer(red colour ka paint hota hai) uski ek
layer lagayee jaa ri hai.aur nina(naina) painting kar ri hai.
4 steps in biotech labs.
1.glycogen phosphorlyase
glycogen+pi->g1p+Glycogen
at:VAC.
VAc ko khola to usmein se bahut saari badbu(fus) bahar aayi and uske andar bahut saara fur
rakha hua tha,jo ek dande(1) par latka hua tha.fusfur.
2.debranching:
mol bio ki lab entry par,jahan humein microbio ke paper dikhaaye gaye the.
phoshorylase stops 4 residues prior to the 1,6 link.
tranferase:transfers 3 residues
alpha-1,6-glucosidase releases the single glucose unit.
hexokinase phophorylates it.
stop->tranfer->release->fusfur.
1.so as you were going to the biochem lab,you stop at the mol bio lab and say:whats it?
2.andar jaa kar,you see ki sink ke pass,kissi teacher ka tranfer order pada hua hai.
3.you were happy ki ye biochem teacher ka hai,but then see ki ye to agle saal ka hai.so you
release it.you release it to the other side,sidase.
4.the room suddenly became smelly(fus) and you decide to go away as the lab ass comes to
with a hockey stick.(6=>hexokinase)
(ab mujhe mat kehna,what can i do,jab phosphorlyation ka fus hi ban paata hai)
3.phosphogluco mutase
g1p->g6p.
cold storage mein,GMO 39 pada hua hai.woh mutant variety hai.
4.G6p->g+pi
done by glucose 6 phoshatase.
transported out by GLUT 2.
how dearly you wish ki biochem lab phat jaaye,with all teachers inside.
Von girke's disease
lack of glucose-6-phosphatase.
so glucose-6p cannot be released as glucose into the blood.
glycogenesis
from washing areain biotech labs to the mtech labs.
overall reaction
glycogen(n)+UDP-glucose->glycogen(n+1)+UDP
by glycogen synthase
by the idea of Hi(a teacher..name confidential) the washing area would also serve as a south
indian resturant.so uska naam udippi(UDP) rakh diya gaya.wahan ki main dish glucond hoti
hai.aur peehce music dene ke liye synthsizer(synth) ka bhi ue kiya jaa raha hai.
part of reactions:
UTP+glucose->UDP glucose+PPi
by UDP glucose pyrophosphorylase
thermo labki entry pe.spagetti hair khada hai(wohi tissue paper and water waala,jiski beti
ki shaadi thi).
uske bete ka Unit test(UT-P) aane waala hai,to woh uski copy le kar khada hai.aur fankee k
paer("pyro"phosphatase) padta hai,to teach his son some english.(what did you just said?)
PPi->2Pi
by inorganic pyrophosphatase
instumentation lab ki entry par,woh dantne waala lab ass khada hai(wahi jiske saamne bharoon
ne psst pss..idhar aa kiya tha).
so you say to him to let you "in",aur sirf itna sunte hi woh bhi tumhaare paer par gir
kar,phat jaata hai.
branching is done by glycosyl-(4-6)-transferase
at:jahan par pittete rakhe hote hain.
us pippete stand emin ek jagah hockey(6) padi hoti hai,aur ek jagah chair(4),to teacher aake
bolti hai,uko interchange kardo,i.e.,transfer kardo,kyunki woh khud ni kar sakti,unke ghar
mein koi "ill"(glyco"syl")hai.
new glycogen cannot be formed without primer.
primer banaane ka enzyme:glycogenin
mircowave par zung lagne lagta hai to uspar primer(red colour ka paint hota hai) uski ek
layer lagayee jaa ri hai.aur nina(naina) painting kar ri hai.
Thursday, September 25, 2008
maarna mat..glycolysis
okies..isme mnemonics(memory ke drame) ka ek aur method use hoga for digits..called shape number method..based on similarity of shapes with digits..like:
6=hockey stick
1=danda
3=heart
2=duck
abhi k liye inna hi...
the glycolysis cyle as follows:
maggi corner to lrc
Glucose(G)
glucon d ka dabba at maggie corner.maggie mein glucon d dal raha hai.
G6p
gate par.hockey kehl rahe hain humaare gaurds.
f6p
oat.hockeyeeyaan lati hui hai on the 'F'ans
f16p
administration ka office.fans par danda and hockey dono.
g3p+dhap
std booth.
dhappa khelte hue log.ek ko lag jaati hai and he starts crying using glycerine(glyceraldehyde) ke jhoote aansoon.sko ulti aane lagti hai..aur woh "heart" pe haath maar maar kar..ghae ghae karne lagta hai.
13bpg
main area mein baithne waale phatte.
ek danda lekar,heart surgery ho ri hai.
fankee kar raha hai.
3pg
photocopy ke side ji jagah.heart pada hua hai,aur woh minnat kar raha hai ketan se ki use hostel mein rehne de,kyunki woh "PG" mein rehte rehte bore ho gaya hai.
2pg
photocopy ki dukaan.ek battak photocopy machine ke oopar baithi hai.
pep
notice bored.registrars message giving some "pep" talk!
p
lrc ke gate par.paru..(c3) waala is waiting.
paru wait!
alchol fermentation
p>A>Eth
pyruvate decaroxylase
alcohol dehyrogenase
lactic acid fermentation
p>lactate
lactate dehydrogenase.
entry points for fructose and galactose
fructose
1.f>f1p>g+dhap>g3p+dhap
fructokinase,frucose-1-phosphate aldolase,triose kinase.
i stored this in my almirah.
bottom most khaana,to top most "parchatti".
fan,fan danda,rota hua baccha(glyceraldehyde),rota hua baccha with ghae.
2.galactose
gal>gal-1-p>UDP gal>UDP glu
4 drawers:
galla(tijori),galla danda,udippi(south indian galla),udippi glucon d.
galactokinase,galactose 1p uridyl transferase,UDP gal 4 epimerase.
g-1-p->g-6-p
phosphoglucomutase
chee sameer!
6=hockey stick
1=danda
3=heart
2=duck
abhi k liye inna hi...
the glycolysis cyle as follows:
maggi corner to lrc
Glucose(G)
glucon d ka dabba at maggie corner.maggie mein glucon d dal raha hai.
G6p
gate par.hockey kehl rahe hain humaare gaurds.
f6p
oat.hockeyeeyaan lati hui hai on the 'F'ans
f16p
administration ka office.fans par danda and hockey dono.
g3p+dhap
std booth.
dhappa khelte hue log.ek ko lag jaati hai and he starts crying using glycerine(glyceraldehyde) ke jhoote aansoon.sko ulti aane lagti hai..aur woh "heart" pe haath maar maar kar..ghae ghae karne lagta hai.
13bpg
main area mein baithne waale phatte.
ek danda lekar,heart surgery ho ri hai.
fankee kar raha hai.
3pg
photocopy ke side ji jagah.heart pada hua hai,aur woh minnat kar raha hai ketan se ki use hostel mein rehne de,kyunki woh "PG" mein rehte rehte bore ho gaya hai.
2pg
photocopy ki dukaan.ek battak photocopy machine ke oopar baithi hai.
pep
notice bored.registrars message giving some "pep" talk!
p
lrc ke gate par.paru..(c3) waala is waiting.
paru wait!
alchol fermentation
p>A>Eth
pyruvate decaroxylase
alcohol dehyrogenase
lactic acid fermentation
p>lactate
lactate dehydrogenase.
entry points for fructose and galactose
fructose
1.f>f1p>g+dhap>g3p+dhap
fructokinase,frucose-1-phosphate aldolase,triose kinase.
i stored this in my almirah.
bottom most khaana,to top most "parchatti".
fan,fan danda,rota hua baccha(glyceraldehyde),rota hua baccha with ghae.
2.galactose
gal>gal-1-p>UDP gal>UDP glu
4 drawers:
galla(tijori),galla danda,udippi(south indian galla),udippi glucon d.
galactokinase,galactose 1p uridyl transferase,UDP gal 4 epimerase.
g-1-p->g-6-p
phosphoglucomutase
chee sameer!
Friday, September 12, 2008
lecture ke chutkule!
aaj ke jokes:
1.varun waala mast!
bacchon ko daaraane ke liye mostly kehte hain...bahar mat jaana nahi to baba aa jayega.
to ek baar,aise hi ek bacche ko bachpan mein khoob daraya gaya.
jab woh bada ho gaya,uski shaadi ho gayee,
tab uski biwi usse kehti...
mujhe kahin ghumaane bahar le chalo
banda:nahi..bahar nahi jaana..baba aa jayega.
biwi:nahi..nahi..woh to bachpan mein hota tha..tumhe daraane ke liye.ab tum bade ho gaye ho.
banda:to kya hua?BABA bhi to bada ho chuka hoga.
2.pd waala
the teacher scheduled an extra class on monday 5-6.to some of our people protested ki mam hum logon ko 2 baje free ho jaana hota hai..
how we protested:
mam,hum to aapko apna samajte the.aisi baatein apno ko shobha nahi deti.
3.mast waala fanky ka...
biochem mein,ek baby ki photo thi,and uska poora digestive system bata rakha tha.she was explaining about lactose intolerance.
teacher wanted us to read the slide and then tell..
beta ye kya hai?
fankee:baaaaaaaby!
then she said...ki when lactose intolerant ppl,take some form of lactose,
some part of it gets accumulated in the digestive tract and then due to the microbial culture in the intestine,it gets rotten away to produce gastrointestinal problems..
me and fanky look to each other..and say to cut a long story short...
GAS!!
1.varun waala mast!
bacchon ko daaraane ke liye mostly kehte hain...bahar mat jaana nahi to baba aa jayega.
to ek baar,aise hi ek bacche ko bachpan mein khoob daraya gaya.
jab woh bada ho gaya,uski shaadi ho gayee,
tab uski biwi usse kehti...
mujhe kahin ghumaane bahar le chalo
banda:nahi..bahar nahi jaana..baba aa jayega.
biwi:nahi..nahi..woh to bachpan mein hota tha..tumhe daraane ke liye.ab tum bade ho gaye ho.
banda:to kya hua?BABA bhi to bada ho chuka hoga.
2.pd waala
the teacher scheduled an extra class on monday 5-6.to some of our people protested ki mam hum logon ko 2 baje free ho jaana hota hai..
how we protested:
mam,hum to aapko apna samajte the.aisi baatein apno ko shobha nahi deti.
3.mast waala fanky ka...
biochem mein,ek baby ki photo thi,and uska poora digestive system bata rakha tha.she was explaining about lactose intolerance.
teacher wanted us to read the slide and then tell..
beta ye kya hai?
fankee:baaaaaaaby!
then she said...ki when lactose intolerant ppl,take some form of lactose,
some part of it gets accumulated in the digestive tract and then due to the microbial culture in the intestine,it gets rotten away to produce gastrointestinal problems..
me and fanky look to each other..and say to cut a long story short...
GAS!!
Subscribe to:
Posts (Atom)
