learn Glycogenolysis and glycogenlysis

Glycogenolysis

4 steps in biotech labs.

1.glycogen phosphorlyase
glycogen+pi->g1p+Glycogen

at:VAC.
VAc ko khola to usmein se bahut saari badbu(fus) bahar aayi and uske andar bahut saara fur

rakha hua tha,jo ek dande(1) par latka hua tha.fusfur.



2.debranching:
mol bio ki lab entry par,jahan humein microbio ke paper dikhaaye gaye the.

phoshorylase stops 4 residues prior to the 1,6 link.

tranferase:transfers 3 residues
alpha-1,6-glucosidase releases the single glucose unit.
hexokinase phophorylates it.

stop->tranfer->release->fusfur.
1.so as you were going to the biochem lab,you stop at the mol bio lab and say:whats it?

2.andar jaa kar,you see ki sink ke pass,kissi teacher ka tranfer order pada hua hai.

3.you were happy ki ye biochem teacher ka hai,but then see ki ye to agle saal ka hai.so you

release it.you release it to the other side,sidase.

4.the room suddenly became smelly(fus) and you decide to go away as the lab ass comes to

with a hockey stick.(6=>hexokinase)

(ab mujhe mat kehna,what can i do,jab phosphorlyation ka fus hi ban paata hai)



3.phosphogluco mutase
g1p->g6p.

cold storage mein,GMO 39 pada hua hai.woh mutant variety hai.



4.G6p->g+pi
done by glucose 6 phoshatase.
transported out by GLUT 2.

how dearly you wish ki biochem lab phat jaaye,with all teachers inside.


Von girke's disease

lack of glucose-6-phosphatase.
so glucose-6p cannot be released as glucose into the blood.





glycogenesis

from washing areain biotech labs to the mtech labs.

overall reaction
glycogen(n)+UDP-glucose->glycogen(n+1)+UDP
by glycogen synthase

by the idea of Hi(a teacher..name confidential) the washing area would also serve as a south

indian resturant.so uska naam udippi(UDP) rakh diya gaya.wahan ki main dish glucond hoti

hai.aur peehce music dene ke liye synthsizer(synth) ka bhi ue kiya jaa raha hai.


part of reactions:

UTP+glucose->UDP glucose+PPi
by UDP glucose pyrophosphorylase

thermo labki entry pe.spagetti hair khada hai(wohi tissue paper and water waala,jiski beti

ki shaadi thi).
uske bete ka Unit test(UT-P) aane waala hai,to woh uski copy le kar khada hai.aur fankee k

paer("pyro"phosphatase) padta hai,to teach his son some english.(what did you just said?)


PPi->2Pi
by inorganic pyrophosphatase
instumentation lab ki entry par,woh dantne waala lab ass khada hai(wahi jiske saamne bharoon

ne psst pss..idhar aa kiya tha).

so you say to him to let you "in",aur sirf itna sunte hi woh bhi tumhaare paer par gir

kar,phat jaata hai.



branching is done by glycosyl-(4-6)-transferase
at:jahan par pittete rakhe hote hain.

us pippete stand emin ek jagah hockey(6) padi hoti hai,aur ek jagah chair(4),to teacher aake

bolti hai,uko interchange kardo,i.e.,transfer kardo,kyunki woh khud ni kar sakti,unke ghar

mein koi "ill"(glyco"syl")hai.



new glycogen cannot be formed without primer.
primer banaane ka enzyme:glycogenin

mircowave par zung lagne lagta hai to uspar primer(red colour ka paint hota hai) uski ek

layer lagayee jaa ri hai.aur nina(naina) painting kar ri hai.